When you have a “cold” or upper respiratory infection (URI), you are going to feel under the weather, of course. You may have a sore or irritated throat, cough, congestion in the sinuses, runny or stuffy nose, easy fatigue, and sometimes even a fever. However, most URIs are caused by a virus, and after 5-7 days, the symptoms are usually significantly improved.
Unfortunately, most of us are very impatient, and after 2-3 days of symptoms, too many of us go to the doctor specifically to get a prescription for an antibiotic. Because antibiotics are specifically meant to kill bacteria, they have absolutely no effect on viruses. When people start improving after taking an antibiotic, they assume that it is the effect of the antibiotic. However, by the time they start taking the antibiotic, from about day 2-4 of illness, the viral infection is just starting to get better.
Interestingly, the antibiotic azithromycin (Zpak), is one of the mostly commonly prescribed antibiotics for URIs. It so happens that this antibiotic has an anti-inflammatory effect, in addition to it’s antibacterial quality. Therefore, it reduces inflammation related to an infection, and symptoms improve as a result, independent of the antibacterial activity. This anti-inflammatory effect misleads the patient to believe that the antibiotic has sped up the resolution of their illness. A pure anti-inflammatory drug such as Aleve may have done the same thing, without killing good bacteria in the body, like the antibiotic does.
There are times when URIs are a bit more sinister. Occasionally, the cause of the infection is bacterial to begin with. More commonly however, the infection started out viral, but then after several days, there is superimposed bacterial infection. This is because the inflamed tissues from the viral infection, are more susceptible to bacterial invasion and infection.
Below are 6 clues that bacteria may be causing your URI and you may need antibiotics:
1 – Symptoms are starting to get worst after 7 days of being ill, PLUS there is thick, cloudy mucous coming from the nostril(s).
2 – You are still ill after 10 days (not worst, but there have been no signs of improvement), PLUS there is thick cloudy mucous from the nostril(s).
3 – It is painful to swallow PLUS there is fever >100.4‘F PLUS there are tender nodes/glands in the neck. This usually indicates a bacterial pharyngitis (such as “strep throat”). Usually there is no cough in this situation.
4 – There is facial pain and/or redness, especially if it is on one side. This may indicate bacterial infection of one of the sinuses (cheek pain from maxillary sinusitis, or forehead pain from frontal sinusitis).
5 – Swelling of any part of the face may indicate serious infection of deep structures. For example swelling around the eye suggests spread of bacterial infection from the sinus to the tissues around the eye socket. Swelling at the jaw may be a sign of spread of bacterial infection from the throat or tonsils, to the deeper tissues, extending to the neck.
6 – Confusion may indicate that a person is seriously ill, probably septic from severe infection. Alternatively, confusion may arise if someone had a sinus infection that spread to the brain. This is a serious complication requiring urgent medical attention.
Most healthy persons will experience no problems with a viral URI. The elderly, and people known to have a weakened immune system should be more vigilant when it comes to managing a URI. When in doubt, you should always contact your primary health care provider, who will be able to evaluate your individual risk and treat accordingly.
What do you think? Do you tend to get anxious after being ill for only 2-3 days? Do you frequently take antibiotics for URIs? Please comment below!
Marie says
April 28, 2016 at 11:36 amGreat article doc! I’m sure this will help to allay anxiety for some of us who start to panics after three days of symptoms! Thanks!
infectiousmd says
April 29, 2016 at 1:53 amYou are welcome Marie! The thing is, most of us have pretty good immune systems and we should give our bodies more credit. We do have the ability to fight most of these infections, if we just give ourselves a chance. Thanks for reading!
Zakia says
April 28, 2016 at 3:56 pmI think I would tend to panic after 5 days if I felt no improvement after 5 days. Now I’ll know to wait until the 7 day point. Thanks a lot for this. Also after how many days is it considered safe to go back to work (no longer a source of infection)?
infectiousmd says
April 29, 2016 at 2:11 amThanks for reading Zakia! To be honest, the 5 or 7 day cut off is not set in stone, it’s an estimate based on the average person’s recovery. Generally speaking however, if you are able to carry out all your activities as usual without excessive fatigue, and certainly, if you are eating (having a good appetite is always a good sign) but you still have symptoms that are more annoying than anything, you are most likely ok without antibiotics.
In terms of going to work, unless you have a fever or feel terribly ill, you don’t have to stay off work at all. Just be sure to maintain cough etiquette and wash/sanitize hands frequently. As long as you go out of your way to not spread germs to coworkers, I don’t think anyone will really have a problem. For healthcare workers like me, we wear masks when we go to examine patients, if we are having a cough or runny nose.
Influenza virus infection is a bit different since it can cause more life threatening complications to more people. People are infectious with influenza virus for about 7 days and should stay at home for that length of time.
Darrel Smith says
April 28, 2016 at 9:32 pmValuable info. Tnx Doc.
infectiousmd says
April 29, 2016 at 2:12 amI am glad you find the information on the blog valuable Darrel! Thank you very much for reading.
Janis Nicholas Elijah says
April 29, 2016 at 12:23 amShould we give antibiotics to babies as young as two months.
infectiousmd says
April 29, 2016 at 2:20 amThank you for your question Janis! I am not a pediatrician, but I do know that any baby with persisting high fever should see a doctor for further evaluation. Babies have very immature immune systems so it is very easy for them to get severe infections. Hopefully however, a 2 month old baby is being exclusively breastfed. I find it sad that so many people don’t breastfeed babies any more. The truth is, breast milk is the best antibiotic, antiviral, etc, for a baby. Vital nutrients and antibodies from the mother are passed through to the baby via breast milk, to greatly reduce the baby’s chance of getting any infection. Thank you for supporting the blog!